The CD3 zeta Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD247, CD3 zeta, CD3-eta, CD3Q, and TCR zeta chain. This antibody recognizes Human, Mouse, and Rat antigen. The CD3 zeta Antibody has been validated for the following applications: Immunocytochemistry, and Western Blot.
Description
Background: CD3 is composed of five invariant polypeptide chains that associate to form three dimers. The five invariant chains of CD3 are labeled gamma, delta, epsilon, zeta, and eta. CD3-zeta forms either homodimers or heterodimers with CD3-eta. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Loss of the zeta chain results in the synthesis of unstable TCRs